Description for Tev-Tropin

Tev-Tropin® [somatropin (rDNA origin) for injection], a polypeptide of recombinant DNA origin, has 191 amino acid residues and also a molecular bodyweight of about 22,124 daltons. It's an amino acid sequence similar to that of human progress hormone of pituitary origin. Tev-Tropin is usually a strain of Escherichia coli modified by insertion from the human advancement hormone gene.
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Tev-Tropin is usually a sterile, white, lyophilized powder, supposed for subcutaneous administration, right after reconstitution Using the accompanying diluent.

Tev-Tropin five mg vial incorporates recombinant somatropin 5 mg and mannitol thirty mg. The 5 mg vial is provided in a mix deal with the accompanying 5 mL vial of diluting solution. The diluent is made up of bacteriostatic 0.nine% sodium chloride injection, USP, (ordinary saline), 0.nine% benzyl Liquor for a preservative, and drinking water for injection.
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Tev-Tropin ten mg vial has recombinant somatropin 10 mg, mannitol 10 mg, disodium phosphate dodecahydrate three.fifty seven mg, and sodium dihydrogen phosphate dehydrate 0.79 mg. The ten mg vial is equipped in a combination offer using an accompanying one mL syringe of diluting Answer. The diluent has bacteriostatic h2o for injection with 0.33% metacresol to be a preservative.

Tev-Tropin is actually a hugely-purified preparation. Reconstituted options have a pH within the range of 7.0 to 9.0.